• 22
  • November
    2011

A new study conducted by the Fox Chase Cancer Center has determined that a certain gene mutation may make individuals more susceptible to mesothelioma.

Doctor Joseph Testa discovered the mutation on gene BAP1 and led the study that tested families with high rates of mesothelioma for the mutation. He discovered that every family member with mesothelioma had the BAP1 gene mutation. In addition, the study found that 25 percent of individuals with no family history of mesothelioma also had the gene mutation.

Mesothelioma is a cancer caused by exposure to asbestos and erionite fibers. Erionite is an asbestos-like fiber that is found in the volcanic ash and other rock formations in at least 12 different states. Mesothelioma is difficult to diagnose since its early symptoms are vague and are often overlooked. This leads to a delay in diagnosis, which is often confirmed when the cancer is already in stages three or four. Typically, mesothelioma causes death within six to nine months of diagnosis.

The discovery of the gene mutation could potentially change the way mesothelioma is tested and diagnosed. Now, patients with family histories of mesothelioma can get tested for the mutation and take the necessary precautions to avoid developing the disease.

Someone with the BAP1 gene mutation may want to avoid work involving asbestos or erionite fibers, or, if a career change is impossible, take extra preventative measures, like consistently using protective equipment and taking showers after contact with the fibers. Those most at risk for developing mesothelioma are construction and factory workers, miners, insulation manufacturers and car mechanics.

For those who work with asbestos or erionite fibers, it may also be prudent to schedule regular physicals that include tests and x-rays on the lungs. These tests, in addition to CAT scans, MRIS and biopsies, are some of the procedures used to diagnose mesothelioma, and may enable physicians to catch mesothelioma in its earlier stages.

Even if someone discovers that he or she has the BAP1 mutation and takes preventative measures against mesothelioma, it is still possible that he or she may contract the disease. Since most cases of mesothelioma result from exposure to asbestos or erionite fibers at the workplace, patients may be eligible for compensation. If mesothelioma patients can prove that they were exposed to asbestos or erionite fibers while on the job, employers may be responsible for their workers' medical care costs, past and future wages, and noneconomic damages like loss of enjoyment of life and emotional distress.

If you or a loved one has been diagnosed with mesothelioma and you suspect that workplace exposure to asbestos may be the cause, contact an experienced personal injury attorney to explore applicable compensation to which you may be entitled.